Henry Markram says the mysteries of the mind can be solved -- soon. Mental illness, memory, perception: they're made of neurons and electric signals, and he plans to find them with a supercomputer that models all the brain's 100,000,000,000,000 synapses....

"Bonk" author Mary Roach delves into obscure scientific research, some of it centuries old, to make 10 surprising claims about sexual climax, ranging from the bizarre to the hilarious. (This talk is aimed at adults. Viewer discretion advised.)...

Refugee and immigrants rights attorney Melanie Nezer shares an urgently needed historical perspective on the crisis at the southern US border, showing how citizens can hold their governments accountable for protecting the vulnerable. "A country shows strength through...

When humanity first landed on the moon in 1969, the typeface Futura was right there with them. In this fascinating history of typography, designer Douglas Thomas shares Futura's role in launching the Apollo 11 spacecraft -- and how it became one of the most used fonts...

In a series of witty punchlines, Patrick Chappatte makes a poignant case for the power of the humble cartoon. His projects in Lebanon, West Africa and Gaza show how, in the right hands, the pencil can illuminate serious issues and bring the most unlikely people...

A handful of people working at a handful of tech companies steer the thoughts of billions of people every day, says design thinker Tristan Harris. From Facebook notifications to Snapstreaks to YouTube autoplays, they're all competing for one thing: your attention....

Doesn't it seem like a lot of online news sites have moved beyond reporting the news to openly inciting your outrage (and your page views)? News analyst Sally Kohn suggests — don't engage with news that looks like it just wants to make you mad. Instead, give your...

Ethan Lindenberger never got vaccinated as a kid. So one day, he went on Reddit and asked a simple question: "Where do I go to get vaccinated?" The post went viral, landing Lindenberger in the middle of a heated debate about vaccination and, ultimately, in front of a...

Do you think you're good at spotting fake videos, where famous people say things they've never said in real life? See how they're made in this astonishing talk and tech demo. Computer scientist Supasorn Suwajanakorn shows how, as a grad student, he used AI and 3D...

Why can we find geometric shapes in the night sky? How can we know that at least two people in London have exactly the same number of hairs on their head? And why can patterns be found in just about any text — even Vanilla Ice lyrics? PatrickJMT describes the Ramsey...

Economist Andrew McAfee suggests that, yes, probably, droids will take our jobs -- or at least the kinds of jobs we know now. In this far-seeing talk, he thinks through what future jobs might look like, and how to educate coming generations to hold them....